No, there is no way to predict when a slot machine is going to hit a jackpot or to determine which machine is going to be lucky.

Pick Slots With The Highest Return To Player (RTP) Percentage. If you're looking for slot machines that are most likely to hit, a good starting point would be finding ones that have the highest percentage of RTP. This is because the higher the RTP percentage, the more likely the slot machine is to pay out.